Certification Process

The Glycemic Research Institute® provides global Claim Substantiation and Certifications in the fields of the Glycemic Index, Diabetes, Cephalic Response, Adipose Tissue Fat-Storage, and Childhood Obesity (Kid-Friendly).

Products that are accepted for Certification are limited to orally ingested foods, beverages, Nutraceutical, and Pharmaceuticals.

Products that are accepted into the GRI Certification Program will undergo Board Approved Human In Vivo Clinical Trials. Test Foods (products) that pass the clinical protocols qualify to display the GRI Government Certification Marks on products labels and brochures, and to make specific claims. All Clinical Trials are based on FDA CFR21 Guidelines.

A Clinical Studies Coordinator will be assigned to work one-on-one with the client.

Why Diet Sodas Are Fattening

For as long as humans have lived on Earth, they have been eating foods that taste sweet, such as sugar cane and honey. So, the brain has a conditioned response in reaction to eating something sweet. It is called the Cephalic Phase Insulin Response (CPIR), and it’s responsible for the fat-storing effects of diet beverages, including diet sodas, diet tea, coffee, energy drinks, sports drinks, and flavored waters. This adaptation in humans is a reaction to the ingestion of sweet-tasting foods. The body learned to associate sweet-taste on the tongue with the resulting sugar-energy-load that landed in the stomach.

The brain came to perceive sweet-taste with the need to program the liver to prepare for the arrival of an outside source of high energy – sugar. As the tongue senses something sweet, it programs the brain to set into motion a series of biochemical events. It doesn’t matter if the sweet taste comes from natural honey or from artificial sweeteners.

This biochemical cascade triggers the liver to stop the manufacture of protein and starch from its body-reserves, and to begin to store the glucose-energy that circulates in the blood.

In the case of diet beverages, the sweet taste sets these events into motion. But when no calories actually appear in the stomach, this causes the body to demand real food, with resulting hyper-urges from the liver to overeat, or to drink more of the sweet-tasting liquid, and the cascade repeats itself.

Almost instantly, the body starts producing insulin, the “fat” hormone, which stores sugar in the blood stream, and programs the adipose tissue fat cells (belly fat) to store, store, store.

This Cephalic Phase Insulin Response (CPIR) creates reactive hypoglycemia (low blood sugar), which further triggers strong cravings for more sweet-tasting items, and high glycemic foods.

After the taste buds are activated by a sweet-taste, the urge to ingest food can last from 1 to 2 hours. So, you are hungry for hours, because no real food or calories has satiated the body’s need for energy.

And now, the body is producing insulin for no reason, because the brain has instructed the liver to store instead of burn/release its storage supplies.
The result is fat, fat, fatter – the Cephalic Fat Spiral.

CBS News Story: Diet Sodas Are Fattening

Tonight on CBS News, Katie Couric, broke the story that diet sodas are fattening and can increase risk of Metabolic Syndrome and heart disease. This was startling news to the public, and baffling to scientists.
Susan Feely, President of the American Beverage Association, stated “How can something with zero calories that’s 99% water with a little flavoring in it . . cause weight gain?” CBS quoted studies that show people who drink more than one soft drink a day had a 48 percent increased prevalence of metabolic syndrome.


New studies involving over 1,500 subjects have shown that people who drink diet soft drinks don’t lose weight – in fact, they gain weight. Researchers stated “What was surprising was when we looked at people only drinking diet soft drinks, their risk of obesity was even higher.”

In fact, when the researchers took a closer look at their data, they found that nearly all the obesity risk from soft drinks came from diet sodas. There was a 41 percent increase in risk of being overweight for every can or bottle of diet soft drink a person consumes a each day.